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Oxidative stress measurement - HealthOX

HEALTHOX

Our test for measuring oxidative stress, the fundamental biochemical parameter of metabolism and health.

WHAT IS oxidative stress?

With each breath, we inhale air containing 21% oxygen. As health professionals, we know that oxygen is fundamental to life. All of our cells consume oxygen in the mitochondria to generate energy, or ATP, needed for biological processes.With aging, and some metabolic diseases, mitochondrial respiration deteriorates and increases in reactive oxygen and nitrogen species (ROS/RNS) arise, which if not detoxified by enzymes and antioxidant compounds give rise to oxidative stress. This has the ability to oxidize, and therefore damage, many cellular components such as proteins, sugars, the mitochondria themselves, even genes, and chromosomes, causing mutations and DNA damage..

Telomeres, at the end of our chromosomes, essential for longevity and cancer prevention, are particularly sensitive to oxidative stress because oxidative stress breaks them and shortens them, generating senescent cells.

However, a healthy level of some ROS/RNS, is necessary for biological processes such as in the defense of the immune system against pathogens, or the maintenance of the endothelial and vascular system.

WHAT ARE FREE RADICALS?

Free radicals are chemical compounds that are highly reactive with all biological substances. They are generated both internally by metabolism, and also by exposure to external agents such as solar radiation, medical and cosmic radiation, tobacco, or chemical pollution, among others.

In general, we can state that an excess of free radicals and oxidative stress is detrimental to health, and is implicated in a multitude of diseases such as cancer, cardiovascular disease, neurodegenerative diseases such as Alzheimer's or type II Diabetes Mellitus, associated with aging.

WHAT POWER OXIDATIVE STRESS?

Oxidative stress can be potentiated among other things by:

  • Sedentary lifestyles and obesity, which cause the mitochondria to malfunction and produce more free radicals.
  • A diet poor in antioxidants (e.g. carotenes, selenium, vitamins C, E, etc.) due to a lower consumption of foods rich in them, such as tomatoes, broccoli, carrots, strawberries, dark chocolate, etc.
  • Environmental pollution, smoking, smoke, radiation, excessive sunbathing, or the consumption of certain drugs.
  • Viral infections, such as the SARS-CoV-2 virus, which causes Covid and damages DNA.
  • Some medical treatments such as radiotherapy and chemotherapy.

How to counteract the action of free radicals?

The ideal way to counteract the action of free radicals, is as we mentioned before, providing a necessary amount of antioxidants, through diet, or through supplements, vitamins, minerals and exercise. Additionally, our body has antioxidant enzymes, (SOD, Catalase, etc), whose mission is to prevent oxidative damage by detoxifying ROS and free radicals. It is also very important to have a healthy lifestyle and adequate rest in order to repair the damage caused by free radicals..

The importance of early detection of oxidative stress

It is evident that, if we recommend to our patients that they follow certain guidelines in their daily life, such as a balanced and healthy diet, that they provide their organism with adequate antioxidants, that they exercise and rest daily, exercise their brain and avoid bad habits such as smoking, overexposure to sunlight and excessive consumption of alcohol or narcotics, we will be helping them to decrease the number of free radicals in your body. Detecting oxidative stress becomes essential to evaluate the effectiveness of these lifestyle measures, allowing us to monitor and improve their impact on overall health.

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We inform our valued customer community that we have made the difficult decision to close our General Martinez Campos clinic.

However, we want to assure our customers that Life Length will continue to provide its proprietary telomere measurement services and HealthTAV®, HealthOX and HealthNAD+ assays in more than 35 countries. We will also continue to work closely with physicians and clinics committed to personalised medicine, longevity and healthy ageing.

It is a true privilege and honour to have had the opportunity to serve and assist tens of thousands of clients who have placed their trust in our clinic since the beginning of the pandemic. We express our deepest appreciation.

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