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Telomere measurement - HealthTAV®

Discover HealthTAV®, our telomere measurement test.

HealthTAV® is based on our patented TAT® (Telomere Analysis Technology), the most accurate in the world to measure the length of telomeres and the determination of multiple associated variables. Know your cellular health with our advanced technology available in more than 35 countries.

WHAT ADVANTAGES DOES OUR TEST OFFER?

TECHNOLOGY

Our patented TAT® technology based on HT Q FISH (High Throughput Quantitative Fluorescence in situ Hybridization) is the most accurate and scalable technique, the only one capable of measuring each and every telomere of all the cells in the sample.

TELOMERE VARIABLES

Our analysis differs from other alternatives on the market because it allows us to obtain not only the mean telomeric length but also more than 200 variables with diagnostic and clinical applications.

CLINICAL RELEVANCE

By performing this test periodically, it is possible to measure and control the extent to which the aging process is affected by lifestyle and therapeutic interventions, as well as the efficacy and adherence to wellness, prevention and personalized medicine programs.

WHAT INFORMATION HEALTHTAV® PROVIDES

In our test report you will be able to obtain the following clinically relevant information:

TELOMERE LENGTH

We offer you the mean, median, and crucially status of your shortest telomeres, as well as the entire histogram distribution, which are the ones directly related to aging diseases such as some types of cancer, cardiovascular diseases, diabetes, etc.

LONGITUDINAL OF THE RESULTS

It is important to study the evolution of telomere length , which is why each report includes all the measurements carried out with us. We recommend repeating the test annually.

BIOLOGICAL AGE

Through our unique algorithm that uses the results of the measured telomere variables and our extensive database which is organized into gender groups and age ranges.

THE MULTIPLE APPLICATIONS OF HEALTHTAV®

The HealthTAV® test can be applied, among others, as a marker of:

  • General health
  • Biological age
  • Aging
  • Immune system
  • Inflammation
  • Cardiovascular diseases
  • Neurodegenerative diseases
  • Pulmonary fibrosis
  • Dyskeratosis congenita
  • Chronic lymphocytic leukemia
  • Others

Telomere length is closely related to environmental agents such as pollution, stress and lifestyle habits. For this reason, it is especially interesting to demonstrate the impact of medical treatments on the telomeres of patients.

SHOP OUR HEALTHTAV® KIT

Whether you are a doctor or a patient, you can easily buy on our website so that we can send you the extraction kit at home.

North America and Canada

European Union

For the rest of the world and inquiries, write to us at

TELOMERES: THE BEST BIOMARKERS OF OUR AGING

WHAT ARE TELOMERES?

Telomeres are part of DNA and are found at the ends of our chromosomes. Its function is to protect our DNA in each cell division, preventing the chromosome from adhering to another or losing relevant information.

They are made up of repetitions of a pattern of bases (TTAGGG) that do not encode information. The more repetitions, the greater the telomere length.

Over time and with each cell division, our telomeres shorten successively until they reach a point where their length is critical and cells cannot divide anymore, entering apoptosis (programmed cell death). or in senescence (loss of functions) (1).

There are many studies that associate long telomeres and a slower rate of shortening with greater longevity, for example studies carried out in mice with hyper-long telomeres that not only lived 13% longer than those with long telomeres normal, but they accumulated less fat and lived longer (2).

Due to the impact they have at the cellular level, the length of telomeres and their rate of shortening are considered a relevant biomarker of the state of aging of the whole organism.

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WHAT FACTORS DOES THE SHORTENING OF TELOMERES DEPEND ON?

The length of the telomeres is highly variable depending on the species we are talking about. Mice, for example, have longer telomeres than humans, yet they have a life expectancy of about 2 years.

This is because their rate of shortening is much faster than ours: while we lose about 70 base pairs in a year, mice lose 7,000 base pairs at their telomeres (3).

But even within the same species there may be variations in the length and rate of shortening that depend directly on factors such as:

Genetics

Environment

Lifestyle

WHAT IS THE CONSEQUENCE OF HAVING SHORT TELOMERES?

Aging is a natural process that many scientists are beginning to classify as a disease in itself.

This causes multiple pathologies to appear that are directly related to old age, such as:

WHAT CAN WE DO TO PRESERVE OUR TELOMERES?

There are currently multiple studies that are aimed at making our telomeres shorten more slowly or trying to lengthen them.

Associated with telomeres there is an enzyme (protein) that has a fundamental role on telomeres, TELOMERASE.

As telomeres shorten with each cell division, telomerase is able to slightly repair the loss in telomere length (4).

Improving our diet, adequate supplementation, treatments such as the hyperbaric chamber (5) and ozone therapy, can reduce the level of oxidative stress in our organism, improve cell repair mechanisms and prevent our telomeres from shortening more quickly.

  1. Blasco M. (2011). María Blasco: Keeping a cap on cancer and aging. Interview by Caitlin Sedwick. The Journal of cell biology, 192(3), 370–371. https://doi.org/10.1083/jcb.1923pi
  2. Mice with hyper-long telomeres show less metabolic aging and longer lifespans. Miguel A. Muñoz-Lorente, Alba C. Cano-Martin, Maria A. Blasco (Nature Communications, 2019). DOI: 10.1038/s41467-019-12664-x
  3. Telomere shortening rate predicts species lifespan. Kurt Whittemore, Elsa Vera, Eva Martínez-Nevado, Carola Sanpera, Maria A. Blasco (PNAS, 2019). DOI: https://www.pnas.org/cgi/doi/10.1073/pnas.1902452116
  4. Blasco, M. Telomerase beyond telomeres. Nat Rev Cancer 2, 627–633 (2002). https://doi.org/10.1038/nrc862
  5. Hachmo, Y., Hadanny, A., Abu Hamed, R., Daniel-Kotovsky, M., Catalogna, M., Fishlev, G., Lang, E., Polak, N., Doenyas, K., Friedman, M., Zemel, Y., Bechor, Y., & Efrati, S. (2020). Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial. Aging, 12(22), 22445–22456. https://doi.org/10.18632/aging.202188
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DO YOU WANT MORE INFORMATION?

For further information or enquiries please contact info@lifelength.com or leave your details on this form.

We inform our valued customer community that we have made the difficult decision to close our General Martinez Campos clinic.

However, we want to assure our customers that Life Length will continue to provide its proprietary telomere measurement services and HealthTAV®, HealthOX and HealthNAD+ assays in more than 35 countries. We will also continue to work closely with physicians and clinics committed to personalised medicine, longevity and healthy ageing.

It is a true privilege and honour to have had the opportunity to serve and assist tens of thousands of clients who have placed their trust in our clinic since the beginning of the pandemic. We express our deepest appreciation.

If you have any questions or queries, please do not hesitate to write to us at info@lifelength.com. We are here to help you in any way we can.

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