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Telomere and telomerase analysis technology

Life Length provides advanced and accurate services in telomere measurements and diagnostics

Our proprietary, cutting-edge technology for a comprehensive Telomere Analysis
through determination of multiple Telomere Length variables.

TAT DETERMINES

  • Mean and Median Telomere Length
  • Lowest 20th percentile Telomere Length
  • % short telomeres
  • % of cells with short telomeres
  • Full Telomere Length histogram distribution
  • Absolute measurements in base pairs

KEY FACTS

  • Clinically Validated (CLIA and ISO 15189)
  • Simultaneous processing of hundreds of samples (384 plates)
  • Can be performed on any cell type
  • Intra-assay coefficient of variation <5%
  • Seven control cell lines
  • Each sample is run in quintuplicate
  • Thousands of telomeres measured per sample
  • High throughput quantitative fluorescence in situ hybridization technology (HT Q-FISH)

 

 

TAT can process multiple types of samples.

Some examples are:

  • Blood
  • Stem Cells
  • Fibroblast cells
  • Sperm
  • Solid tumors
  • Several tissue samples
  • Bone marrow

SAMPLE REQUIREMENTS

 

Telomerase is the enzyme that can elongate telomeres and it can be used as an independent biomarker or in combination with other Telomere variables. The Q-TRAP assay measures the activity of the telomerase enzyme.

KEY FACTS

  • Clinically Validated (CLIA and ISO 15189)
  • Simultaneous processing of hundreds of samples (384 plates)
  • Each sample is run in triplicate
  • Ideal for screening telomerase inhibitor and/or activator compounds
  • Full study report with statistical analysis
  • Quantitative Telomeric Repeat Amplification Protocol Technology (Q-TRAP)

Q-TRAP can process different types of samples

Some examples are: Blood, any type of stem cell, fibroblast cells, cancer cells, etc.

SAMPLE REQUIREMENTS

 

An alternative Telomere Length assay ideal for isolated DNA samples.

KEY FACTS

  • Relative and absolute telomere length measurements (T/S ratio and in base pairs)
  • Simultaneous processing of hundreds of samples (384 plates)
  • Each sample is run in triplicate
  • Applicable for purified isolated DNA of any biological sample
  • Optimized for human sample processing

 

SAMPLE REQUIREMENTS

 

The “Gold Standard” assay for Telomere Length determination.

KEY FACTS

  • Up to 12 samples simultaneously
  • Each sample is run three times
  • Telomere length measured in base pairs
  • Applicable for purified isolated DNA of any biological sample
  • Terminal Repeat Fragmentation technology (TRF)

SAMPLE REQUIREMENTS